Which Treatment Should Be Given To Which Infertility Cases?

Which Treatment Should Be Given To Which Infertility Cases?

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Infertility can place a huge burden on your emotional health, but if you are infertile and hope to have a baby, there are many options to hope for. Science continues to evolve, treatment options are getting better, and more babies are born each year using one of the techniques listed below. In fact, more than half of couples with infertility can get pregnant after treatment, and this does not include high-tech and expensive treatments such as IVF.

Which Treatment Should Be Given To Which Infertility Cases?

Which technique you will need depends on your cause of infertility. How much it will cost may also vary depending on some factors such as where you live.

Fertility Pills

How it works: These drugs, taken in injection or pill form, secrete ovulation-initiating hormones to increase egg production and make the uterus more suitable for embryo placement.

Good for: Women who do not ovulate regularly and in cases of spouses with poor sperm quality. Avoid if there is scarring from endometriosis with damaged or blocked fallopian tubes.

Success rates: 40-45% of women who take the pills and ovulate become pregnant, and those with injections have success rates up to 50%.

Pros: These drugs are often the first choice in infertility treatment because of their low cost and easy use.

Cons: Bloating, headaches, hot flushes and nausea. Side effects are worse with needles and multiple births, premature births and the formation of large ovarian cysts can occur.

Artificial Insemination

How it works: Specially crafted sperm is inserted directly into the uterus using a thin, flexible instrument and is the most common fertility method. If you choose this method, your doctor may ask you to increase your chances of fertilization by taking fertility pills.

Good for: It is good if the man’s sperm motions are slow or the quality is low and the sperm count is low. It is also used in women who produce antibodies against their partner’s sperm, or in women whose vaginal fluid is too dense, acidic or insufficient for sperm to reach the egg.

Success rates: It depends on the age of the woman and the quality of the sperm of the man, but generally there is a success rate of 15-20% in each trial, a success rate of around 60-70% after 6 attempts.

Pros: Simple procedure that can be done in the doctor’s office.

Cons: May cause multiple births depending on possible side effects of fertility pills.

IVF Treatment

How it works: It is a multi-step process, during which your eggs are collected and fertilized with sperm in the laboratory. When embryos develop, one or two are implanted in the uterus, while the rest are stored.

Good for: Women with endometriosis scars, blocked or severely damaged fallopian tubes, and older people. Also in cases of unexplained infertility couples and men with very low sperm quality.

Success rates: Depends on age. 41% of women under the age of 35, 32% of those aged 35-37, and 23% of those aged 38-40 become pregnant.

Pros: Couples with serious fertility problems can become parents.

Cons: The treatment is costly and physically tiring. Also before each try fertility drug may require use.


How it works: The surrogate mother carries the baby for another woman. With artificial insemination, the surrogate mother becomes pregnant, meanwhile, the couple’s embryo is used, such as the father’s sperm or in vitro fertilization.

Good for: Mothers who are unable to carry a baby due to illness, hysterectomy or infertility. In rare cases, it can be used if both partners are infertile.

Success rates: Depends on egg and sperm quality. On average, the live birth rate is around 5% -30% per trial.

Pros: Couples with fertility problems can achieve pregnancy.

Cons: Costs are high. Couples may feel like there is no pregnancy. In addition, they have to deal with many legal obligations.

Reproductive System Surgery

How it works: Anatomical defects, scars and occlusions are treated with surgery in both men and women.

Good for: couples diagnosed with a disease or abnormality.

Success rates: Depends on discomfort and severity, as well as age. One study found that women who received laparoscopic treatment for endometriosis had twice as many pregnancy rates as those who did not receive this treatment.

Pros: If we ignore the pain and discomfort associated with the disease, it can increase the likelihood of pregnancy.

Cons: Some surgeries are more extensive than others, which increases the risk, cost, and rest period.

Gamete Intrafallopian Transfer

How it works: Eggs are collected from the female, mixed in the petri dish containing the male’s sperm and then transferred directly to the fallopian tubes where fertilization will take place.

Good for: In cases where at least one fallopian tube is working in the woman or when the man has poor mobility with a low sperm count. In addition, those who refuse in vitro fertilization treatment due to religious and moral reasons and those who have inexplicable infertility.

Success rates: 25-30% pregnancy is achieved in one trial, young, healthy women are more likely to succeed.

Pros: Allows fertilization to occur in a natural environment.

Cons: There is no immediate confirmation that fertilization has occurred. It is more complicated than IVF treatment because laparoscopy is required to place eggs and sperm in the tubes. If more than one egg is used, which usually happens, the risk of multiple births is higher than normal.

Zygote Intrafallopian Transfer

How it works: It’s like an IVF treatment, but in this case the embryo is transferred to the fallopian tubes, not the uterus.

Good for: Couples with unexplained infertility or low sperm count in men. The woman must have at least one tube open or have ovulation problems.

Success rate: As with most assisted reproductive techniques, it depends on age and health. Generally, 36% of those who try to get pregnant, 29% give birth.

Pros: The fertilization of the egg-sperm mixture is known before it is placed in the fallopian tubes. Therefore, fewer eggs can be used, which reduces the risk of multiple births.

Cons: Since the laparoscope is used, it is an intrusive operation, which increases the risks and costs compared to other treatments. This method and gamete intrafallopian transfer method are rarely used.

Source: Prof. Dr. Bulent Shave